발표논문

제목 [암성 골 통증] 암성 골 통증에 대한 동물모델 연구 현황
암성 골 통증에 대한 동물모델 연구 현황
Current studies of acupuncture in cancer-induced bone pain animal models
저자 강동경희대병원 의료진 : 백용현(공동), 서병관(교신저자), 박연철(공동)
타기관 의료진 : 유희경
저널명 Evidence-Based Complementary and Alternative Medicine
게재일 2014.10.14
논문소개 Acupuncture is generally accepted as a safe and harmless treatment option for alleviating pain. To explore the pain mechanism, numerous animal models have been developed to simulate specific human pain conditions, including cancer-induced bone pain (CIBP). In this study, we analyzed the current research methodology of acupuncture for the treatment of CIBP. We electronically searched the PubMed database for animal studies published from 2000 onward using these search terms: (bone cancer OR cancer) AND (pain OR analgesia) AND (acupuncture OR pharmacopuncture OR bee venom). We selected articles that described cancer pain in animal models. We analyzed the methods used to induce cancer pain and the outcome measures used to assess the effects of acupuncture on CIBP in animal models. We reviewed articles that met our inclusion criteria. Injection of mammary cancer cells into the cavity of the tibia was the most frequently used method for inducing CIBP in the animal models. Among the eight selected studies, five studies demonstrated the effects of electroacupuncture on CIBP. The effects of acupuncture were assessed by measuring pain-related behavior. Future researches will be needed to ascertain the effectiveness of acupuncture for treating CIBP and to explore the specific mechanism of CIBP in animal models.
페이지 URL http://www.hindawi.com/journals/ecam/2014/191347/abs/

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