발표논문

제목 [기능성 소화불량증] 기능성 소화불량증 환자의 소화불량 증상과 위 운동성에 반하사심탕이 미치는 효과: 무작위, 이중맹검, 위약 대조군, 2기관 연구
기능성 소화불량증 환자의 소화불량 증상과 위 운동성에 반하사심탕이 미치는 효과: 무작위, 이중맹검, 위약 대조군, 2기관 연구
The Effects of Banha-sasim-tang on Dyspeptic Symptoms and Gastric Motility in Cases of Functional Dyspepsia: A Randomized, Double-Blind, Placebo-Controlled, and Two-Center Trial
저자 박재우, 고석재, 한가진, 여인권, 류봉하, 김진성
저널명 Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 265035, 10 pages
게재일 2013.05.19.
논문소개
-초록정리
Introduction : Functional dyspepsia (FD) is highly prevalent, and no standard treatments exist for this condition. Herbal prescriptions are widely used to treat FD. In traditional Korean medicine, Banha-sasim-tang (BST) is a famous herbal prescription for dyspepsia. This study aimed to evaluate the efficacy of BST and to examine the relationship between gastric slow waves and dyspeptic symptoms.

Materials and Methods : In total, 100 FD patients were recruited; BST or placebo was administered for 6 weeks. The gastrointestinal symptom scale, FD-related quality of life scale, and frequency or power variables regarding gastric slow waves were measured at 0, 6, and 14weeks.

Results : There were no significant differences in the overall dyspeptic symptoms or quality of life between the BST and placebo groups. However, early satiety was significantly improved in the BST group (P = 0.009, at 6 weeks by intention-to-treat analysis). Abnormal gastric dysrhythmias and power ratios were also significantly improved by BST.

Conclusion : BST had no significant effects on FD. However, early satiety appeared to improve after BST administration. Electrogastrography may be a useful technique for assessing changes in gastric motility dysfunction after interventions for FD. Further investigation focused on specific symptoms or subtypes of FD is required.
페이지 URL http://www.hindawi.com/journals/ecam/2013/265035/
연구가 가지는 의의 본 연구는 표준적 치료법이 없는 기능성 소화불량증에 한약인 반하사심탕을 이용하여 그 효과를 검증한 논문으로서 double blind되는 한약 placebo를 이용하였다는 점과 위의 운동성을 관찰할 수 있는 위전도를 이용하였다는 점에서 의의가 있다고 할 수 있다. 위 연구를 통해 반하사심탕이 기능성 소화불량증 환자의 조기 포만감과 불규칙적인 위의 리듬을 개선시켰다는 점을 알 수 있다.

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