발표논문

제목 [기억력 장애] 고치법이 기억력 장애를 가진 노인들의 기억력에 미치는 영향에 대한 fMRI 연구
고치법이 기억력 장애를 가진 노인들의 기억력에 미치는 영향에 대한 fMRI 연구
An fMRI study on the effects of jaw-tapping movement on memory function in elderly people with memory disturbances
저자 강동경희대병원 의료진 : 박정미(교신저자), 조승연(1저자), 장건호(공동), 박성욱(공동), 고창남(공동)
타기관 의료진 : 정우상(공동), 문상관(공동), 조기호(공동)
저널명 European Journal of Integrative Medicine 2014;6(1):90-97
게재일 2014.02.
논문소개
-초록정리
Introduction : Mild cognitive impairment (MCI) is distinguishable from the memory loss associated with normal aging and may represent an early stage of Alzheimer's disease. This study sought to determine whether jaw-tapping could be a useful exercise to improve memory function by observing changes in brain activity.

Methodology :Twelve subjects with subjective memory complaints (SMC group) and thirteen MCI patients (MCI group) participated in a prospective functional magnetic resonance imaging (fMRI) study. All subjects performed jaw-tapping and n-back memory tasks during blood oxygen level dependent (BOLD) fMRI. Measurements were made before and after home practice of the jaw-tapping exercise for 4 weeks. Pre- and post-test fMRI data were analyzed using statistical parametric maps of brain activation.

Results : The SMC and the MCI groups showed improvement in the memory task after 4 weeks of jaw-tapping training. In the SMC group, more brain regions were activated overall, including the prefrontal, temporal, and precuneus regions related to memory function. Although fewer brain regions were activated in the MCI group compared to the SMC group, brain activity increased in the MCI group after 4 weeks of training.

Conclusion : Jaw-tapping movement could be a useful exercise for improving memory and cognitive function in elderly people with memory disturbance by stimulating brain regions related to these function.
페이지 URL http://www.sciencedirect.com/science/article/pii/S1876382013001649

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