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제목 [뇌영상] 남녀의 뇌 편도체 중심핵 크기 차이에 대한 연구
남녀의 뇌 편도체 중심핵 크기 차이에 대한 연구
Sex differences in amygdala subregions; Evidence from subregional shape analysis
저자 강동경희대병원 의료진 : 박정미(공동), 조승연(공동)
타기관 의료진 : 조경구(교신저자), 김형준(1저자), 김남국(공동), 김세현(공동), 홍석준(공동), 박경모(공동), 임사비나(공동), 나병조(공동), 채윤병(공동), 이정찬(공동), 여수정(공동), 최일환(공동)
저널명 Neuroimage 2012;60(4):2054-2061
게재일 2012.05.01.
논문소개
-초록정리
Each subregion of the amygdala is characterized by a distinct cytoarchitecture and function. However, most previous studies on sexual dimorphism and aging have assessed differences in the structure of the amygdala at the level of the amygdala in its entirety rather than at the subregional level. Using an amygdala subregional shape analysis, we investigated the effects of sex, age, and the sex × age interaction on the subregion after controlling for intracranial volume. We found the main effect of age in the subregions and the effect of sex in the superficial nucleus, which showed that men had a larger mean radius than women. We also found a sex × age interaction in the centromedial nucleus, in that the radius of the centromedial nucleus showed a steeper decline with age in women compared with men. Regarding the amygdala volume as a whole, we found only an age effect and did not find any other significant difference between genders. The sex difference in the amygdala subregion and its relevance to the circulating gonadal hormone were discussed.
페이지 URL http://www.sciencedirect.com/science/article/pii/S1053811912002029

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